nonsense mutation meaning in Chinese
无意义突变
无义突变:基因发生突变,使编码区中的某个密码子变为无义密码子。
Examples
- The nature of all the three mutant alleles of this group is nonsense mutation disrupting the coding region of oxt gene
该组的三个突变体等位基因的突变都是无义突变,它们都破坏了。 xt基因的编码区。 - The sequence result showed that the nature of pygo mutant alleles f66 , f15 - 108 and f126 were nonsense mutation , which probably led to truncated pro
测序结果表明其中h个突变体等位基因f66 , f15 108和f126均是无义突变。 - The products were used in rflp analysis . we found the g849a nonsense mutation that was responsible for the se enzyme inactivation in shandong han chinese and mongolian of inner mongolia individuals was in the same frequency , 0 . 55 %
结果在两个人群中均发现了一个携带g849a点突变的个体,该点突变产生的无功能等位基因se ~ ( 849 )在两个人群中的频率均是0 . 55 。 - Analysis of the sequence variation of cytochrome b gene indicated that there is no evidence of insertions or deletions , i . e . , they are all of identical length of 1143 bp in all the sequences of cytochrome b gene . further , the sequences can be fully translated into amino acid using chicken mitochondrial codon without nonsense mutations or intervening stop codons . the 1143 bp cytochrome b alignment contained 416 variable sites , of which 306 were parsimony informative sites with the strongest variable in third codon positions and less variable in first and second codon positions
细胞色素b基因序列变异分析表明: 1 )雁形目鸟类细胞色素b基因全序列长度一致,无插入和缺失:对照鸡线粒体密码子系统全序列能全部翻译成氨基酸序列,无无义突变,全序列内部无终止密码子; 2 )序列比对后1143加,含416个核着酸变异位点, 306个简约信息位点,其中处于密码子第三位的变异最大,第一位和第二位碱基的变异相对较小。 - The nature of the mutant alleles is either nonsense mutation or the mutation which disrupted the splicing of the primary transcripts . anti - en antibody staining and in situ hybridization on sll germline clone ( glc ) embryo using wg antisense probe showed defective en protein bands and defective wg transcripts bands
通过对sll生殖系克隆胚胎进行的抗engrailed ( en )抗体染色和wg反义探针的原位杂交结果表明,与野生型果蝇的胚胎相比较, en蛋白和wg转录物条带出现了明显的缺失。